Test Compendium

Test Compendium is your definitive resource for detailed information on a wide array of diagnostic tests. Each entry in our compendium is meticulously cataloged to aid healthcare providers in selecting and interpreting the right tests for their patients.

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Displaying 1 - 25 of 352

FISH ALK

FISH

FISH ALK Methodology FISH Test Description Probes ALK(Non-Heme) Disease Non-small cell lung cancer, and neuroblastomaALK Rearrangement by FISH is designed to detect loss rearrangement (breakapart) of the


Ki67

Immunohistochemistry (IHC)

Ki67 Methodology Immunohistochemistry (IHC) Test Description Disease Breast Cancer Lymphomas (NHL)Marker of cell proliferation. Labile, nonhistone nuclear protein expressed in G1, S, G2 and M phases


PgR

Immunohistochemistry (IHC)

PgR Alternative Name Progesterone Receptor Methodology Immunohistochemistry (IHC) Test Description Disease Breast cancerEstrogen and progesterone act through intra-nuclear receptors, ER and PR, which belong


TP53

Immunohistochemistry (IHC)

TP53 Methodology Immunohistochemistry (IHC) Test Description Disease Li-Fraumeni Syndrome, breast cancer, osteosarcoma, soft tissue sarcoma, some leukemias and lymphomas, papilloma of choroid plexus, brain


ER

Immunohistochemistry (IHC)

ER Alternative Name Estrogen Receptor Methodology Immunohistochemistry (IHC) Test Description Disease Breast CancerEstrogen and progesterone act through intra-nuclear receptors, ER and PR, which belong


EBER (ISH)

In Situ Hybridization (ISH)

EBER (ISH) Alternative Name Epstein-Barr Virus by ISH Methodology In Situ Hybridization (ISH) Test Description Disease EBERs are abundantly expressed during persistent infection, including EBV-associated


Kappa

In Situ Hybridization (ISH)

Kappa Alternative Name Kappa by ISH Methodology In Situ Hybridization (ISH) Test Description Disease Plasma cell dyscrasias (MM,MGUS,WM), some lymphoid neoplasms, amyloidosisHuman lg-kappa CISH Probe is


Lambda

In Situ Hybridization (ISH)

Lambda Alternative Name Lambda by ISH Methodology In Situ Hybridization (ISH) Test Description Disease Plasma cell dyscrasias (MM,MGUS,WM), some lymphoid neoplasms, amyloidosisLambda mRNA CISH Probe is


ALK (Lymphoma)

FISH

ALK (Lymphoma) Alternative Name Anaplastic lymphoma kinase, (2p23) Methodology FISH Test Description Probes ALK (2p23) Disease This gene has been found to be rearranged, mutated, or amplified in a series


FGFR1/D8Z2

FISH

FGFR1/D8Z2 Alternative Name FISH Eosinophilia probe Methodology FISH Test Description Probes FGFR1/D8Z2 (8p12/8p11.1-q11.1) Disease Myeloproliferative neoplasm, Osteoglophonic Dysplasia, squamous cell


FIP1L1/CHIC2/PDGFRA

FISH

FIP1L1/CHIC2/PDGFRA Alternative Name FISH Eosinophilia probe Methodology FISH Test Description Probes FIP1L1/CHIC2/PDGFRA (4q12) Disease Myeloid and/or lymphoid neoplasms associated with eosinophilia and


PDGFRB

FISH

PDGFRB Alternative Name FISH Eosinophilia probe Methodology FISH Test Description Probes PDGFRB (5q32-q33) Disease Myeloid and/or lymphoid neoplasms associated with eosinophilia and PDGFRB abberations,


PCM1/JAK2

FISH

PCM1/JAK2 Alternative Name FISH Eosinophilia probe Methodology FISH Test Description Probes PCM1/JAK2 (8p22/9p24.1) Disease Myeloid and lymphoid neoplasms with eosinophilia and PCM1/JAK2 translocation.PCM:


FISH Eosinophilia Panel

FISH

FISH Eosinophilia Panel Methodology FISH Test Description Probes FGFR1/D8Z2 (8p12/8p11.1-q11.1) & FIP1L1/CHIC2/PDGFRA (4q12) & PCM1/JAK2 (8p22/9p24.1) & PDGFRB (5q32-q33)FGFR1/D8Z2 (8p12/8p11.1-q11.1)


FISH RET

FISH

FISH RET Methodology FISH Test Description Probes RET (10q11.21) Disease Non-small cell lung cancer, Papillary thyroid carcinomaIt is designed to detect chromosomal rearrangements involving the RET proto-oncogene


PTEN Deletion (1p36.31/1q25.3)

FISH

PTEN Deletion (1p36.31/1q25.3) Methodology FISH Test Description Probes 1p36.31/1q25.3 Disease Glial tumors, neuroblastoma, multipl myeloma, MPNDeletions of the 1p36 and 19q13 region genes are seen in


PTEN Deletion (19p13/19q13)

FISH

PTEN Deletion (19p13/19q13) Methodology FISH Test Description Probes 19p13/19q13 Disease Glial tumors, microdeletion/microduplication syndrome at 19p13.3Deletions of the 1p36 and 19q13 region genes are


PTEN Deletions (10q23.2-q23.31/10p11.1-q11.1)

FISH

PTEN Deletions (10q23.2-q23.31/10p11.1-q11.1) Methodology FISH Test Description Probes 10q23.2-q23.31/10p11.1-q11.1 Disease Brain tumors, HNSCC, prostate cancer, melanoma, cervix cancer, endometrium cancer,


Brain Cancer FISH Panel

FISH

Brain Cancer FISH Panel Methodology FISH Test Description Probes (1p36.31/1q25.3 & 19p13.3/19q13.32-q13.33 & 10q23.2-q23.31/10p11.1-q11.1) Disease Brain cancerDeletions of the 1p36 and 19q13 region


KMT2A

FISH

KMT2A Alternative Name Mixed-lineage leukemia (MLL) Methodology FISH Test Description Probes 11q23.3 Disease Wiedemann-Steiner Syndrome and AML with t(9;11), ALLThis gene encodes a transcriptional coactivator


ETV6/RUNX1

FISH

ETV6/RUNX1 Methodology FISH Test Description Probes 12p13.2/21q22.12 Disease Myeloid Malignancy (e.g., AML) and Lymphoid Malignancy (e.g., ALL).ETV6/RUNX1 is the most common fusion gene in childhood ALL.


IGH

FISH

IGH Alternative Name Immunoglobulin heavy chain Methodology FISH Test Description Probes 14q32.33 Disease Plasma Cell Leukemia; B-cell Acute Lymphocytic Leukemia; Chronic Lymphocytic Leukemia (CLL); Multiple


ABL1/BCR

FISH

ABL1/BCR Alternative Name ABL1/BCR fusion gene, Philadelphia chromosome Methodology FISH Test Description Probes 9q34.11-q34.13/22q11.22-q11.23 Disease CML, some ALL and AML (rarely).ABL1/BCR fusion gene


ALL FISH Panel

FISH

ALL FISH Panel Methodology FISH Test Description Probes ( 11q23.3 & 12p13.2/21q22.12 & 14q32.33 & 9q34.11-q34.13/22q11.22-q11.23) Disease Wiedemann-Steiner Syndrome, Plasma Cell Leukemia; B-cell


PML/RARA

FISH

PML/RARA Methodology FISH Test Description Probes 15q24.1/17q12-q21.2 Disease acute promyelocytic leukemia (APL).The PML-RARA fusion is the result of a recurrent, balanced translocation between chromosomes


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