FIP1L1/CHIC2/PDGFRA
Alternative name:
FISH Eosinophilia probe
Methodology
FISH
Test Description and clinical significance
Probes
FIP1L1/CHIC2/PDGFRA (4q12)
Disease:
Myeloid and/or lymphoid neoplasms associated with eosinophilia and PDGFRA abberations.
4q12 Rearrangement (FIP1L1-PDGFRA) – FIP1L1-PDGFRa fusion (rearrangement of 4q12; interstitial deletion of CHIC2 region) is observed in diverse eosinophilia-associated hematologic disorders. The cases with FIP1L1-PDGFRa fusion show an excellent response to the tyrosine kinase inhibitor imatinib mesylate.
Specimen Requirements
Collection:
1~2ml in Green top (Sodium Heparin) tube OR Lavender top (EDTA) tube.
Stability:
120 Hours
Unacceptable Conditions:
DO NOT FREEZE
Storage & Transport
Room Temperature
CPT(s)
88377
New York Approved
YES
TAT
2 Days
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
