FISH RET
Methodology
FISH
Test Description and clinical significance
Probes
RET (10q11.21)
Disease:
Non-small cell lung cancer, Papillary thyroid carcinoma
It is designed to detect chromosomal rearrangements involving the RET proto-oncogene (10q11.21). This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. The RET proto-oncogene encodes a tyrosine kinase receptor and under normal conditions, it functions as a signaling molecule involved in cellular growth and differentiation. Chromosomal rearrangements involving RET were identified in papillary thyroid carcinoma and Non-Small-Cell Lung Cancer (NSCLC) patients
Specimen Requirements
Collection:
FFPET/un-stained slides
Stability:
Indefinitely
Unacceptable Conditions:
Unlabeled specimen/Decalcified tissue/Insuffcient tissue fixation
Storage & Transport
Room Temperature
CPT(s)
88377
New York Approved
YES
TAT
3 Days
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
