PML/RARA
Methodology
FISH
Test Description and clinical significance
Probes
15q24.1/17q12-q21.2
Disease:
acute promyelocytic leukemia (APL).
The PML-RARA fusion is the result of a recurrent, balanced translocation between chromosomes 15 and 17. It provides specific diagnosis, prognostic information, and prediction of relapse when monitoring residual disease of acute promyelocytic leukemia (APL).
NGS AML panel & PML-RARA by PCR are recommended
Specimen Requirements
Collection:
1~2ml in Green top (Sodium Heparin) tube OR Lavender top (EDTA) tube.
Stability:
120 Hours
Unacceptable Conditions:
DO NOT FREEZE
Storage & Transport
Room Temperature
CPT(s)
88377
New York Approved
YES
TAT
2 Days
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
