BCL1
Methodology
Immunohistochemistry (IHC)
Test Description and clinical significance
Disease:
MCL (mantle cell lymphoma), Hairy cell leukemia and plasmacytoma
BCL1/Cyclin D1 is a nuclear protein detectable in the majority of mantle cell lymphomas. Hairy cell leukemia and plasmacytoma may also express BCL1 with a weaker signal. BCL1 is an oncogene acting as a cell cycle regulator. An abnormal BCL1 gene may give rise to a defective Cyclin D1 protein
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods
Storage & Transport
Room Temperature
CPT(s)
88342 if intial single stain or
88341 for each additional stain
New York Approved
NO
TAT
1 Day
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
