Caldesmon
Methodology
Immunohistochemistry (IHC)
Test Description and clinical significance
Disease:
Smooth Muscle Tumors
Caldesmon is a protein that in humans is encoded by the CALD1 gene. It is a smooth muscle specific protein that regulates smooth muscle contraction. This clone recognizes the high-molecular-weight variant (h-caldesmon) and does not react with the non muscle variant. Neither variant of caldesmon is present in skeletal muscle. Anti-h-caldesmon seems to be a reliable marker of smooth muscle differentiation, and may assist in the diagnosis of smooth muscle tumors.
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods
Storage & Transport
Room Temperature
CPT(s)
88342 if intial single stain or 88341 for each additional stain Caldesmon
New York Approved
NO
TAT
1 Day
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
