CD5
Methodology
Immunohistochemistry (IHC)
Test Description and clinical significance
Disease:
Marker for Chronic lymphocytic leukemia (CLL), mantle cell lymphoma (only rarely is CD5-), T cells (normal and malignant), and thymic carcinoma
CD5 is expressed on the surface of all T cells bearing the αβ heterodimer T cell receptor (around 50000 molecules per cell) but is absent or at lower density on the γδ T cell subset. It is present but at lower density (2–10000 molecules per cell) on a minor population of murine and human B cells. CD5 is important in identification of T cells and most T cell lymphomas, some low grade B cell lymphomas, thymic carcinoma
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods
Storage & Transport
Room Temperature
CPT(s)
88342 if intial single stain or 88341 for each additional stain CD5
New York Approved
NO
TAT
1 Day
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
