CD7

Methodology

Immunohistochemistry (IHC)


Test Description and clinical significance

Disease:
T-cell leukemias and myeloid leukemias. CD7 can be aberrantly expressed in refractory anaemia with excess blasts (RAEB) and may confer a worse prognosis. A lack of CD7 expression could insinuate mycosis fungoides (MF) or Sezary syndrome

This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.


Specimen Requirements

Collection:
FFPE/un-stained slides/Fresh tissue in formalin

Stability:
Room temperature

Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods


Storage & Transport

Room Temperature


CPT(s)

88342 if intial single stain or 88341 for each additional stain CD7


New York Approved

NO


TAT

1 Day


*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.

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