CK19
Alternative name:
Cytokeratin 19
Methodology
Immunohistochemistry (IHC)
Test Description and clinical significance
Disease:
Bladder chordoma, CK19+ fragments is a poor prognostic factor for breast cancer, hepatoid adenocarcinoma metastatic to liver, cholangiocarcinoma, poor prognostic factor in hepatocellular carcinoma
Lung: poor prognostic factor for non small cell lung carcinoma, poor prognostic factor in pancreatic endocrine neoplasms, folicular variant papillary thyroid carcinoma
Involved in the organization of myofibers; links contractile apparatus to dystrophin at costameres of striated muscle
Polymorphisms of CK19 pseudogene are associated with primary biliary cirrhosis
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods
Storage & Transport
Room Temperature
CPT(s)
88342 if intial single stain or 88341 for each additional stain CK19
New York Approved
NO
TAT
1 Day
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
