Congo Red
Methodology
Special Stains
Test Description and clinical significance
Disease:
Systemic or localized amyloidosis, progression of multiple myeloma and other plasma cell dyscrasias
Congo red is a direct diazo dye used for staining amyloid in tissue sections (Biosci Rep 2019;39:BSR20181415)
This organic compound forms complexes with the misfolded proteins deposited in amyloidosis; analysis of the emission spectra from these complexes reveals the optical reactivity under polarized light, described as apple green birefringence
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods
Storage & Transport
Room Temperature
CPT(s)
88313
New York Approved
NO
TAT
1 Day
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
