D2-40 (Podoplanin)
Methodology
Immunohistochemistry (IHC)
Test Description and clinical significance
Disease:
Confirmation of lymphovascular invasion, Primary skin adnexal tumors, Chondrosarcoma, Seminoma, mesothelioma, and in situ germ cell neoplasms
Podoplanin is a 40 kDa, transmembrane, oncofetal, O linked sialoglycoprotein (mucin type) found on lymphatic endothelium, mesothelium and fetal testis (also other cells as indicated below)
D2-40 is a monoclonal antibody that reacts to podoplanin
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods
Storage & Transport
Room Temperature
CPT(s)
88342 if intial single stain or 88341 for each additional stain D2-40
New York Approved
NO
TAT
1 Day
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
