EMA

Alternative name:

Epithelial Membrane Antigen


Methodology

Immunohistochemistry (IHC)


Test Description and clinical significance

Disease:
Meningioma, some hematopoietic tumors and malignant mesothelioma, and Marker of Paget disease

EMA (aka MUC1) a glycoprotein that provides barrier function
Overexpression is common in malignancies and leads to tumorigenesis
Immunohistochemical stain is positive in most carcinomas, often used alongside other cytokeratin stains
For noncarcinomas, EMA is useful to distinguish meningioma, some hematopoietic tumors and malignant mesothelioma


Specimen Requirements

Collection:
FFPE/un-stained slides/Fresh tissue in formalin

Stability:
Room temperature

Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods


Storage & Transport

Room Temperature


CPT(s)

88342 if intial single stain or 88341 for each additional stain EMA


New York Approved

NO


TAT

1 Day


*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.

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