Alternative name:
Epithelial Membrane Antigen
Methodology
Immunohistochemistry (IHC)
Test Description and clinical significance
Disease:
Meningioma, some hematopoietic tumors and malignant mesothelioma, and Marker of Paget disease
EMA (aka MUC1) a glycoprotein that provides barrier function
Overexpression is common in malignancies and leads to tumorigenesis
Immunohistochemical stain is positive in most carcinomas, often used alongside other cytokeratin stains
For noncarcinomas, EMA is useful to distinguish meningioma, some hematopoietic tumors and malignant mesothelioma
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods
Storage & Transport
Room Temperature
CPT(s)
88342 if intial single stain or 88341 for each additional stain EMA
New York Approved
NO
TAT
1 Day
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
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