Factor XIIIa
Methodology
Immunohistochemistry (IHC)
Test Description and clinical significance
Disease:
Fibrohistiocytic proliferations, dermal dendrocytes, dermatofibroma or benign fibrous histiocytoma (FH), sebaceous differentiation, and indeterminate leprosy
FXIIIa is widely expressed in a variety of cell types; however, it is most commonly recognized as a marker of fibrohistiocytic proliferations
Derived from monocyte/macrophage myeloid lineage and expressed in dermal dendrocytes, primarily surrounding microvasculature in the adventitial dermis near the dermoepidermal junction and near skin appendages
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods
Storage & Transport
Room Temperature
CPT(s)
88342 if intial single stain or 88341 for each additional stain Factor XIIIa
New York Approved
NO
TAT
1 Day
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
