PRAME
Alternative name:
PReferentially expressed Antigen in MElanoma
Methodology
Immunohistochemistry (IHC)
Test Description and clinical significance
Disease:
Differential diagnoses of benign versus malignant melanocytic lesions, Evaluation of tumor margins in melanoma specimens, Evaluation of sentinel lymph nodes in melanoma cases
PRAME (PReferentially expressed Antigen in MElanoma) is a tumor biomarker expressed in most cutaneous and ocular melanomas as well as various other malignant neoplasms.
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed
for extended periods
Storage & Transport
Room Temperature
CPT(s)
88342, 88341
New York Approved
NO
TAT
24 hours
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
