Unique Identifier:
ML-H009
Name on Requisition:
Myeloid Panel-NGS (DNA only)
Product Line:
HEME
Panel Group:
NGS
Panel Name:
PCR–CML
Methodology
Molecular
NGS
Test Description and clinical significance
Genes
ABL1, ANKRD26, ASXL1, BCOR, BCORL1, BRAF, CBL, CBLB, CBLC, CDKN2A, CSF3R, CUX1, CXCR4, DDX41, DNMT3A, ETNK1, ETV6, EZH2, FBXW7, FLT3, GATA1, GATA2, GNAS, GNB1, HRAS, IDH1, IDH2, IL7R, JAK1, JAK2, JAK3, KIT, KRAS, MPL, MYD88, NF1, NOTCH1, NPM1, NRAS, PAX5, PHF6, PIGA, PPM1D, PRPF8, PTEN, PTPN11, RB1, RUNX1, SETBP1, SF3A1, SF3B1, SH2B3, SMARCB1, SMC1A, SMC3, SRSF2, STAG2, STAT3, STAT5B, TET2, TP53, U2AF1, U2AF2, UBA1, WT1, XPO1, ZRSR2
Disease:
MPN, CMML, MDS
Myeloid Neoplasms NGS Panel (DNA only) is a next-generation sequencing assay designed to detect clinically relevant somatic variants in genes commonly altered in acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), and related hematologic disorders. The panel identifies single nucleotide variants and small insertions/deletions across multiple target genes, providing diagnostic, prognostic, and therapeutic information to support risk stratification and treatment selection.
Specimen Requirements
Preparation:
PB, BM, DNA
Collection:
3ml EDTA, citrate (ACD) or Heparinized whole blood or bone marrow aspirates are transported at room temperature, received with 96 hr, refrigerated are stable for a week from the date of collection, Extracted RNA; a minimum volume of 20 μl at 100ng/μl
Stability:
96hours/4 to 7 days refrigerated
Unacceptable Conditions:
Clotted peripheral blood or bone marrow. Peripheral blood or bone marrow older than a week. Leukophoresis products. Improperly labeled specimens. Improperly stored RNA.
Storage & Transport
Blood or bone marrow specimens should be kept at room temperature and preferably received within 96 hrs of drawing, Previously extracted RNA is acceptable if stored at appropriate temperature short term at -20oC (up to two weeks) or long term at -80oC and should be transported on dry ice.
CPT(s)
81455
New York Approved
Yes
TAT
5
Levels of Service
Full
DexS Code
Z05C4
Prefix
MI
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
