TCRB Gene rearrangement

Unique Identifier:

ML-H012


Name on Requisition:

T-Cell rearrangement Beta


Product Line:

HEME


Panel Group:

PCR


Panel Name:

PCR–Lymphoma


Methodology

Molecular
PCR


Test Description and clinical significance

Genes
TCRB

Disease:
T-cell neoplasm

T-cell Receptor (TCR) Beta Gene Rearrangement, PCR is useful for establishing clonality of T-cell lymphoid neoplasms and identification of minimal residual disease or early recurrence in patients with a previous diagnosis of a T-cell neoplasm. It can be used in association with T-cell receptor (TCR) gamma PCR assay


Specimen Requirements

Preparation:
PB, BM, Fresh tissue, FFBE tissue or slides

Collection:
2 ml of peripheral blood or bone marrow aspirate anti-coagulated with heparin or EDTA, Fresh tissue (5mm) in RPMI or saline, Formalin-fixed paraffin embedded tissue or slides, Body fluids (CSF, pleural or ascetic fluid) in RPMI or without fixative

Stability:
96hours/4 to 7 days refrigerated

Unacceptable Conditions:
Unlabeled or improperly labeled samples, Samples older than stability date, Gross hemolysis, Decalcified specimens or specimens fixed in B5


Storage & Transport

Blood or bone marrow specimens should be kept at room temperature and preferably arrives in the lab within 96 hrs of drawing. Samples that are 4 to 7 days old should be refrigerated. Fresh tissue should be shipped on ice. Body fluids should be shipped within 48 hrs of collection.


CPT(s)

81340


TAT

5


Requisition Type

Heme


Levels of Service

Full


DexS Code

Z047K


Prefix

MI


*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.

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