CALR Mutation Analysis
Unique Identifier:
ML-H015
Name on Requisition:
CALR
Product Line:
HEME
Panel Group:
PCR
Panel Name:
PCR–MPN
Methodology
Molecular
PCR
Test Description and clinical significance
Genes
CALR
Disease:
Essential Thrombocythemia , Primary Myelofibrosis
The calreticulin gene, called CALR , is responsible for making a protein called calreticulin. CALR mutations represent an important hallmark of myeloproliferative neoplasms (MPN), especially essential thrombocythemia and primary myelofibrosis.
Specimen Requirements
Preparation:
PB, BM
Collection:
at least 0.5 mL of DTA, citrate (ACD) or Heparinized bone marrow and peripheral blood specimens
Stability:
96hours/4 to 7 days refrigerated
Unacceptable Conditions:
Unlabeled, Specimen submitted is in the incorrect fixative or anticoagulant, Specimen received after the stability date, Gross hemolysis, Frozen specimen, Insufficient specimen, Left un-refrigerated for an extended period
Storage & Transport
Blood or bone marrow specimens should be kept at room temperature and preferably received within 96 hours of drawing. Samples that are 4 to 7 days old should be refrigerated.
CPT(s)
81219
New York Approved
Yes
TAT
3
Requisition Type
Heme
Levels of Service
Full
DexS Code
ZB77R
Prefix
MI
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
