ER
Alternative name:
Estrogen Receptor
Methodology
Immunohistochemistry (IHC)
Test Description and clinical significance
Disease:
Breast Cancer
Estrogen and progesterone act through intra-nuclear receptors, ER and PR, which belong to the superfamily of steroid hormone receptors. The expression of ER and PR are linked because transcription of the PR gene is induced by estrogen and inhibited by progestins. ER is expressed as two major isoforms, ERa and ERb. This test is used to guide hormone therapy for breast cancer patients.
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed for extended periods
Storage & Transport
Room Temperature
CPT(s)
88360
New York Approved
YES
TAT
1 Day
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
