Pan-Lymphoid Multigene Panel
Unique Identifier:
ML-H030
Name on Requisition:
Lymphoid Multigene Panel
Product Line:
HEME
Panel Group:
NGS
Panel Name:
Multi-Gene NGS Panel >15 genes
Methodology
Molecular
NGS
Test Description and clinical significance
Genes
ATM, BTK, BIRC3, CARD11, CD79B, DDX3X, FBXW7, MAPK1, MYD88, NOTCH1, PIK3CA, PIK3CD, PTEN, PTPN6, SF3B1, TP53, XPO
Disease:
chronic lymphocytic leukemia (CLL), B- and T-cell lymphomas, and plasma cell neoplasms.
Lymphoid Multigene NGS Panel is a next-generation sequencing assay designed to detect clinically relevant mutations in genes recurrently altered in lymphoid malignancies, including chronic lymphocytic leukemia (CLL), B- and T-cell lymphomas, and plasma cell neoplasms. The panel identifies single nucleotide variants and small insertions/deletions across multiple genes, providing diagnostic, prognostic, and therapeutic information that supports risk stratification and selection of targeted therapies.
Specimen Requirements
Preparation:
PB, BM
Collection:
At least 0.5 ml EDTA, citrate (ACD) or Heparinized whole blood or bone marrow aspirates for DNA mutations
Stability:
96hours/4 to 7 days refrigerated
Unacceptable Conditions:
Specimen submitted is in the incorrect fixative or anticoagulant. Specimen received after the stability date. Gross hemolysis. Frozen specimen. Insufficient specimen. Unlabeled. Left un-refrigerated for an extended period.
Storage & Transport
Blood or bone marrow specimens should be kept at room temperature and preferably received within 96 hrs of drawing. Samples that are 4 to 7 days old should be refrigerated. Sufficient quantity of previously extracted DNA is acceptable if stored at appropriate temperature (short term at 2–8oC or long term at -15 to -25 oC) and should be transported on ice.
CPT(s)
81450
New York Approved
Yes
TAT
7
Requisition Type
Heme
Levels of Service
Full
DexS Code
NONE
Prefix
MI
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
