Genes
AKT1, ARAF, ATM, ARID1A, BARD1, BRAF, BRCA1, BRCA2, BRIP1, CCNE1, CDK12, CHEK1, CHEK2, CTNNB1, ERBB2, ESR1, FGFR1, FGFR2, FGFR3, FANCA, FANCL, KIT, MAP2K1, MET, MLH1, MSH2, MSH6, MTOR, NTRK1, NTRK2, NTRK3, NF1, NRG1, PALB2, PIK3CA, PMS2, PPP2R1A, PTEN, RAD51C, RAD51D, RAD54L, RET, TP53.

Disease:
ovarian cancers

The OncoSwift® Ovarian Comprehensive Panel analyzes the genomic landscape of epithelial ovarian cancers. It detects mutations, fusions, and copy number variations, including BRCA1/2 and homologous recombination repair genes, providing diagnostic, prognostic, and therapeutic guidance, especially for PARP inhibitor eligibility.

Preparation:
PB

Collection:
Two tubes of peripheral blood (10mL/tube) are collected in PAXgene Blood ccfDNA tube

Stability:
7 to 10 days at room temperature

Unacceptable Conditions:
Specimen submitted is not in the PAXgene Blood ccfDNA Tubes or n the PAXgene Blood ccfDNA tube after expired date. Insufficient specimen (less than 10 mL whole blood/tube). Specimen is leaking from the collection tube, or the glass tube is broken. Gross hemolysis. Bacterial overgrowth Submitted with incomplete requisition form (unless a requisition is subsequently sent). Unlabeled or improperly labeled specimens, without contact information or when failing to reach the ordering physician for clarification. cfDNA shipped in inappropriate temperature .