EBER (ISH)
Alternative name:
Epstein-Barr Virus by ISH
Methodology
In Situ Hybridization (ISH)
Test Description and clinical significance
Disease:
EBERs are abundantly expressed during persistent infection, including EBV-associated cancers e.g. nasopharyngeal cancer and some lymphomas e.g. Burkitt lymphoma.
Epstein-Barr virus-encoded small RNAs (EBER) test detects the Epstein-Barr virus (EBV) in tissues. During latency of the EBV, up to 11 viral genes are expressed that encode up to nine proteins. Two of these genes are EBER-1 and EBER-2. EBERs are abundantly expressed during EBV related persistent infections and malignancies.
Specimen Requirements
Collection:
FFPE/un-stained slides/Fresh tissue in formalin
Stability:
Room temperature
Unacceptable Conditions:
Unlabeled specimen/specimen left unfixed for extended periods
Storage & Transport
Room Temperature
CPT(s)
88365 for initial single probe,
88364 for each additional.
New York Approved
YES
TAT
2 Days
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
