Probes
(8p11.1-q11.1 & 20q11.21/20q12 & 9q12 & 13q14.2/13q34 & 1p36.31/1q25.3)

Disease:
Myeloproliferative Neoplasms, Myeloproliferative Disorder, Chronic Myelogenous Leukemia, Acute Myeloid Leukemia, MDS, Multiple Myeloma, MPN, CLL, Glial tumors, neuroblastoma

comprehensive panel to detect cytogenetic abnormalities associated with myeloproliferative neoplasms.
Designed to detect copy number variations of the 8p11 region on chromosome 8 and quantitative abnormalities of chromsome 8.
Detection of deletions involving the human PTPRT gene ( Protein tyrosine phosphatase receptor type T) as well as the detection of chromosome 20q11 specific sequences. Deletion of long arm of chromosome 20 [del(20q)] is the second most frequent recurrent chromosomal abnormality in hematological malignancies In patients with myelodysplastic neoplasms (MDS), a 20q deletion [del(20q)] isis associated with a favorable prognosis in MDS.
Designed to detect copy number variations of the 9q12 region on chromosome 9 and quantitative abnormalities of chromsome 9.
Designed to detect chromosomal abnormalities on chromosome 13 ( ch13 deletion/abberations). Chromosome 13q aberrations occur in 16-40% of MM cases - most of them being complete monosomy 13 (85%), whilst the remaining 15% constitute deletion of 13q
Detection of deletion of short or log arms of chromsome 1.
NGS P.vera reflexes JAK2 V617F reflex to exons 12, 13 &15 are recommended

Collection:
1~2ml in Green top (Sodium Heparin) tube OR Lavender top (EDTA) tube/ 10 mL of fluid in RPMI medium, or
1 cm3 marble-sized piece of fresh tumor immersed completely with RPMI medium or sterile saline

Stability:
121 Hours/48 hours

Unacceptable Conditions:
DO NOT FREEZE